Do not use a household spoon because you may not get the correct dose. It is important to continue taking this medication as prescribed even if you feel well. Do not stop taking this medication without consulting your doctor. Some conditions may become worse when this drug is suddenly stopped. Prostacyclin Analogues: May enhance the antiplatelet effect of Agents with Antiplatelet Properties. Hepatic impairment: Use with caution in patients with hepatic impairment; clearance is decreased and plasma concentrations are increased; a lower dosage may be needed. Do not suddenly stop taking fluvoxamine extended-release capsules without checking with your doctor. Side effects may occur. They may include mental or mood changes, numbness or tingling of the skin, dizziness, confusion, headache, trouble sleeping, or unusual tiredness. You will be closely monitored when you start fluvoxamine extended-release capsules and whenever a change in dose is made. ipratropium
Treatment should consist of those general measures employed in the management of overdosage with any antidepressant. Vitamin E Systemic: May enhance the antiplatelet effect of Agents with Antiplatelet Properties. PREGNANCY and BREAST-FEEDING: Fluvoxamine extended-release capsules may cause harm to the fetus if it is taken during the last 3 months of pregnancy. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of taking fluvoxamine extended-release capsules while you are pregnant. Fluvoxamine extended-release capsules are found in breast milk. Do not breast-feed while taking fluvoxamine extended-release capsules.
Dorevitch A, Davis H. Fluvoxamine-associated sexual dysfunction. Methylene Blue: Selective Serotonin Reuptake Inhibitors may enhance the serotonergic effect of Methylene Blue. This could result in serotonin syndrome. Why is this drug prescribed?
Deferasirox: May increase the serum concentration of CYP1A2 Substrates. Pomalidomide: CYP1A2 Inhibitors Strong may increase the serum concentration of Pomalidomide. Management: Avoid when possible. Monitor toxicity closely when combined. In patients also receiving a P-gp inhibitor and strong CYP3A4 inhibitor, reduce pomalidomide dose by 50% Canadian labeling says to reduce dose with any use of a strong CYP1A2 inhibitor. Antiemetics 5HT3 Antagonists: May enhance the serotonergic effect of Serotonin Modulators. This could result in serotonin syndrome. The efficacy of Fluvoxamine Maleate Tablets was established in four trials in outpatients with OCD: two 10-week trials in adults, one 10-week trial in pediatric patients ages 8-17 and one maintenance trial in adults.
Depression Canadian labeling; not an approved use in US labeling: Oral: Immediate release: Initial: 50 mg once daily at bedtime then after a few days may increase to 100 mg daily as tolerated; titrate gradually based on response and tolerability in 50 mg increments; usual dosage range: 100 to 200 mg daily; maximum dose: 300 mg daily. Where can people find more information about depression? Thrombolytic Agents: Agents with Antiplatelet Properties may enhance the anticoagulant effect of Thrombolytic Agents. L fluvoxamine serum levels during maternal therapy with fluvoxamine in dosages of 100 to 150 mg daily. Capsules unless directed to do so by your physician. Prescriptions should be written for the smallest quantity consistent with good patient care. The patient's family or caregiver should be alerted to monitor patients for the emergence of suicidality and associated behaviors such as anxiety, agitation, panic attacks, insomnia, irritability, hostility, impulsivity, akathisia, hypomania, and mania; patients should be instructed to notify their healthcare provider if any of these symptoms or worsening depression or psychosis occur. Fluvoxamine Maleate Tablets can cause sleepiness or may affect your ability to make decisions, think clearly, or react quickly. You should not drive, operate heavy machinery, or do other dangerous activities until you know how Fluvoxamine Maleate Tablets affects you. Do not drink alcohol while using Fluvoxamine Maleate Tablets.
Tell your doctor if you have ever had any unusual or allergic reaction to fluvoxamine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. If your doctor tells you to stop taking fluvoxamine extended-release capsules, you will need to wait for several weeks before beginning to take certain other medicines eg, MAOIs, nefazodone. Ask your doctor when you should start to take your new medicines after you have stopped taking fluvoxamine extended-release capsules. Fluvoxamine Maleate Tablets are indicated for the treatment of obsessions and compulsions in patients with obsessive compulsive disorder OCD as defined in DSM-III-R or DSM-IV. The obsessions or compulsions cause marked distress, are time-consuming, or significantly interfere with social or occupational functioning. Such monitoring should include daily observation by families and caregivers. Serotonin Modulators. The development of serotonin syndrome may occur. Exceptions: Nicergoline; Tedizolid. Tryptophan: Tryptophan may enhance the serotonergic effects of Fluvoxamine, and the combination should, therefore, be used with caution. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of fluvoxamine in the elderly. However, elderly patients are more likely to have hyponatremia low sodium in the blood and liver problems, which may require an adjustment in the dose for patients receiving fluvoxamine. Take LUVOX CR Capsules at night exactly as prescribed. Serotonin syndrome is a possibly fatal syndrome that can be caused by fluvoxamine extended-release capsules. Your risk may be greater if you take fluvoxamine extended-release capsules with certain other medicines eg, MAOIs, "triptans". Symptoms may include agitation; confusion; hallucinations; coma; fever; fast or irregular heartbeat; tremor; excessive sweating; and nausea, vomiting, or diarrhea. Contact your doctor at once if you have any of these symptoms. Of the 1087 OCD and depressed patients treated with Fluvoxamine maleate in controlled clinical trials in North America, 22% discontinued due to an adverse reaction. Adverse reactions that led to discontinuation in at least 2% of Fluvoxamine maleate-treated patients in these trials were: nausea 9% insomnia 4% somnolence 4% headache 3% and asthenia, vomiting, nervousness, agitation, and dizziness 2% each. Pregnant women exposed to antidepressants during pregnancy are encouraged to enroll in the National Pregnancy Registry for Antidepressants NPRAD. Women 18 to 45 years of age or their health care providers may contact the registry by calling 844-405-6185. Enrollment should be done as early in pregnancy as possible. Cyproterone: May decrease the serum concentration of CYP1A2 Substrates. Therefore, coadministration of Phentermine and these drug products is not recommended. astonin
WebMD User Reviews should not be considered as medical advice and are not a substitute for professional medical advice, diagnosis, or treatment. Never delay or disregard seeking professional medical advice from your physician or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences may be a helpful health information resource but they are never a substitute for professional medical advice from a qualified healthcare provider. What is a depressive disorder? Neonates exposed to Fluvoxamine Maleate Tablets and other SSRIs or SNRIs late in the third trimester have developed complications requiring prolonged hospitalization, respiratory support, and tube feeding and may be at risk for persistent pulmonary hypertension of the newborn PPHN. Fluvoxamine maleate incidence was equal to or less than placebo are not listed in the table above. CR Capsules and clozapine are used concurrently. mail order generic cardura visa cardura
Apixaban. Specifically, the risk for bleeding may be increased. Management: Carefully consider risks and benefits of this combination and monitor closely. Rarely, males may have a painful or prolonged erection lasting 4 or more hours. If this occurs, stop using this drug and get medical help right away, or permanent problems could occur. Elderly patients and those with hepatic impairment have been observed to have a decreased clearance of Fluvoxamine maleate. Consequently, it may be appropriate to modify the initial dose and the subsequent dose titration for these patient groups. LUVOX CR Capsules will harm your unborn baby. It is important to continue taking this medication even if you feel well. Do not stop taking this medication without consulting your doctor. Some conditions may become worse when this drug is suddenly stopped. Luvox does not cause dependency, however withdrawal symptoms may occur if a patient stops taking Luvox suddenly. To avoid withdrawal, the dosage should be tapered gradually. Take this medication by mouth with or without food as directed by your doctor. Concurrent use with alosetron, pimozide, ramelteon, thioridazine, or tizanidine; use of MAO inhibitors intended to treat psychiatric disorders concurrently or within 14 days of discontinuing either fluvoxamine or the MAO inhibitor; initiation of fluvoxamine in a patient receiving linezolid or intravenous methylene blue. What are the types of depression, and what are depression symptoms and signs? These reactions are listed in order of decreasing rates in the OCD trials. Some side effects can be serious. great drontal
In the tabulations which follow, a standard COSTART-based Dictionary terminology has been used to classify reported adverse reactions. If the COSTART term for a reaction was so general as to be uninformative, it was replaced with a more informative term. The frequencies presented, therefore, represent the proportion of the 2737 patient exposures to multiple doses of Fluvoxamine maleate who experienced a reaction of the type cited on at least one occasion while receiving Fluvoxamine maleate. Only some people are at risk for these problems. Greater risks for developing a discontinuation syndrome have been associated with antidepressants with shorter half-lives, longer durations of treatment, and abrupt discontinuation. For antidepressants of short or intermediate half-lives, symptoms may emerge within 2 to 5 days after treatment discontinuation and last 7 to 14 days APA, 2010; Fava, 2006; Haddad, 2001; Shelton, 2001; Warner, 2006. Do not start Fluvoxamine Maleate Tablets in a patient who is being treated with linezolid or intravenous methylene blue because there is an increased risk of serotonin syndrome. Trabert W, Hohagen F, Winkelmann G, et al. A seizure, and electroencephalographic signs of a lowered seizure threshold, associated with fluvoxamine treatment of obsessive-compulsive disorder. Pharmacopsychiatry 1995; 28: 95-7. Phentermine hydrochloride equivalent to 30 mg Phentermine base. The pooled analyses of placebo-controlled trials in children and adolescents with MDD, obsessive compulsive disorder OCD or other psychiatric disorders included a total of 24 short-term trials of 9 antidepressant drugs in over 4400 patients. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Phentermine hydrochloride equivalent to 30 mg of Phentermine base. Vemurafenib: May increase the serum concentration of CYP1A2 Substrates. Management: Consider alternatives to such combinations whenever possible, particularly if the CYP1A2 substrate has a relatively narrow therapeutic index. The effectiveness of Fluvoxamine Maleate Tablets for the treatment of obsessive compulsive disorder OCD was demonstrated in two 10-week multicenter, parallel group studies of adult outpatients. Dose adjustment in adolescents up to the adult maximum dose of 300 mg may be indicated to achieve therapeutic benefit. Nonteratogenic Effects: Neonates exposed to Fluvoxamine Maleate Tablets and other SSRIs or serotonin and norepinephrine reuptake inhibitors SNRIs late in the third trimester have developed complications requiring prolonged hospitalization, respiratory support, and tube feeding. Such complications can arise immediately upon delivery. Reported clinical findings have included respiratory distress, cyanosis, apnea, seizures, temperature instability, feeding difficulty, vomiting, hypoglycemia, hypotonia, hypertonia, hyperreflexia, tremor, jitteriness, irritability, and constant crying. These features are consistent with either a direct toxic effect of SSRIs and SNRIs or, possibly, a drug discontinuation syndrome. The effectiveness of Fluvoxamine Maleate Tablets for the treatment of OCD was also demonstrated in a 10-week multicenter, parallel group study in a pediatric outpatient population children and adolescents, ages 8 -17. Check with your pharmacist about how to dispose of unused medicine. DULoxetine: CYP1A2 Inhibitors Strong may increase the serum concentration of DULoxetine. Crewe HK, Lennard MS, Tucker GT, et al. The effect of selective serotonin re-uptake inhibitors on cytochrome P4502D6 CYP2D6 activity in human liver microsomes. Br J Clin Pharmacol 1992; 34: 262-5. shop epogen capsules
Cigarette smoking decreases blood levels of this medication. Tell your doctor if you smoke or if you have recently stopped smoking. Ensure an adequate airway, oxygenation, and ventilation. Monitor cardiac rhythm and vital signs. General supportive and symptomatic measures are also recommended. Induction of emesis is not recommended. Gastric lavage with a large-bore orogastric tube with appropriate airway protection, if needed, may be indicated if performed soon after ingestion, or in symptomatic patients. Swallow the capsules whole. not crush or chew the capsules. Doing so can release all of the drug at once, increasing the risk of side effects. Your healthcare provider will want to see you often while you are taking fluvoxamine, especially at the beginning of your treatment. Be sure to keep all appointments for office visits with your doctor. Tryptophan: May enhance the serotonergic effect of Selective Serotonin Reuptake Inhibitors. This may cause serotonin syndrome. Panobinostat: May increase the serum concentration of CYP2D6 Substrates. Management: Avoid concurrent use of sensitive CYP2D6 substrates when possible, particularly those substrates with a narrow therapeutic index. Do not drink alcohol while you are using fluvoxamine extended-release capsules. Erlotinib: FluvoxaMINE may increase the serum concentration of Erlotinib. Management: Avoid use of this combination when possible. When the combination must be used, monitor the patient closely for the development of severe adverse reactions, and if such severe reactions occur, reduce the erlotinib dose in 50 mg decrements. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take fluvoxamine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. buy condyline nyc condyline
What about self-help and home remedies for depression? Tryptophan may cause severe vomiting. LCR 150 on the other side of the cap. Comparisons of Fluvoxamine maleate and placebo groups in separate pools of short-term OCD and depression trials on 1 mean change from baseline on various ECG variables and on 2 incidence of patients meeting criteria for potentially important changes from baseline on various ECG variables revealed no important differences between Fluvoxamine maleate and placebo. C and high humidity dampness. Infrequent: gastrointestinal hemorrhage and melena; Rare: hematemesis. Tell your doctor or pharmacist if you are taking other products such as alcohol, antihistamines such as cetirizine, diphenhydramine other drugs for sleep or anxiety such as alprazolam, zolpidem muscle relaxants such as carisoprodol, cyclobenzaprine and narcotic pain relievers such as codeine, hydrocodone. Thyroid Products: Selective Serotonin Reuptake Inhibitors may diminish the therapeutic effect of Thyroid Products. Thyroid product dose requirements may be increased. Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. nimodipine
Bertschy G, Vandel S, Vandel B, et al. Fluvoxamine-tricyclic antidepressant interaction: an accidental finding. Eur J Clin Pharmacol 1991; 40: 119-20. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Immediate release: Initial: 50 mg once daily; may increase in 50 mg increments at intervals of at least 1 week; usual dosage range: 100 to 300 mg daily Asakura, 2007. Do not take an MAOI within 2 weeks of stopping Fluvoxamine Maleate Tablets unless directed to do so by your physician. Yale-Brown Obsessive Compulsive Scale CY-BOCS total score of 24. Patients receiving Fluvoxamine maleate experienced mean reductions of approximately six units on the CY-BOCS total score, compared to a three-unit reduction for placebo patients. RxList is part of the WebMD Health Network. The opinions expressed in the WebMD User Reviews are solely those of the User, who may or may not have medical or scientific training, and do not represent the opinions of WebMD. These member reviews have not been reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other purpose except for compliance with our Terms and Conditions. Cohen LJ, DeVane CL. Clinical implications of antidepressant pharmacokinetics and pharmacogenetics. Ann Pharmacother 1996 Dec; 303: 1471-80. HYDROcodone: CYP3A4 Inhibitors Weak may increase the serum concentration of HYDROcodone. Patients should be advised that taking Fluvoxamine Maleate Tablets can cause mild pupillary dilation, which in susceptible individuals, can lead to an episode of angle closure glaucoma. Pre-existing glaucoma is almost always open-angle glaucoma because angle closure glaucoma, when diagnosed, can be treated definitively with iridectomy. Open-angle glaucoma is not a risk factor for angle closure glaucoma. Some MEDICINES MAY INTERACT with fluvoxamine extended-release capsules.
Capsules before you start taking it and each time you get a refill. What about sexual dysfunction related to antidepressants? Studies have not been performed with Phentermine to determine the potential for carcinogenesis, mutagenesis or impairment of fertility. Fluvoxamine Maleate Tablets are available in 25 mg, 50 mg and 100 mg strengths for oral administration. In addition to the active ingredient, Fluvoxamine maleate, each tablet contains the following inactive ingredients: carnauba wax, hypromellose, mannitol, polyethylene glycol, polysorbate 80, pregelatinized starch potato silicon dioxide, sodium stearyl fumarate, starch corn and titanium dioxide. The 50 mg and 100 mg tablets also contain synthetic iron oxides. Read the Guide provided by your before you start using and each time you get a refill. If you have any questions, consult your doctor or pharmacist. Using fluvoxamine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Use caution in prescribing Phentermine for patients with even mild hypertension risk of increase in blood pressure. The 25mg tablets: carnauba wax, hypromellose, mannitol, polyethylene glycol, polysorbate 80, pregelatinized starch potato silicon dioxide, sodium stearyl fumarate, starch corn and titanium dioxide. Several weeks may pass before your symptoms improve. Do NOT take more than the recommended dose, change your dose, or use fluvoxamine extended-release capsules for longer than prescribed without checking with your doctor. buy feldene overseas
Canadian labeling: Additional contraindications not in US labeling: Hypersensitivity to fluvoxamine or any component of the formulation; concurrent use with astemizole, cisapride, mesoridazine, or terfenadine. The 50mg and 100mg tablets: In addition to the above inactive ingredients, contain synthetic iron oxides. At first, 50 milligrams mg once a day at bedtime. Your doctor may adjust your dose as needed. However, the dose is usually not more than 300 mg per day. If your daily dose is higher than 100 mg, your doctor may want you to take it in 2 divided doses. What is the most important information I should know about Fluvoxamine Maleate Tablets? Minerals with ADEK, Folate, Iron: May enhance the antiplatelet effect of Agents with Antiplatelet Properties. No evidence of dependency phenomena was found. Agents with Antiplatelet Properties. Bleeding may occur. Combinations containing any of the following medications, depending on the amount present, may also interact with this medication. For Nursing Mothers: Luvox is secreted in human breast milk. The decision of whether to discontinue nursing or to discontinue the drug should take into account the potential for serious adverse effects to the nursing infant as well as the potential benefits of Luvox to the mother. Jeffries J, Bezchlibnyk-Butler K, Remington G. Amenorrhea and galactorrhea associated with fluvoxamine in a loxapine-treated patient. J Clin Psychopharmacol. isaca.info amlodipine
Kristensen JH, Hackett LP, Kohan R et al. The amount of fluvoxamine in milk is unlikely to be a cause of adverse effects in breastfed infants. J Hum Lact. TraMADol. The risk of seizures may be increased. TraMADol may enhance the serotonergic effect of Serotonin Modulators. This could result in serotonin syndrome. For a listing of dosage forms and brand names by country availability, see Dosage Forms sections. Methadone: May enhance the serotonergic effect of FluvoxaMINE. This could result in serotonin syndrome. FluvoxaMINE may increase the serum concentration of Methadone. Therefore, -feeding is not recommended while using this drug. Consult your doctor before breast-feeding. Phentermine is related chemically and pharmacologically to the amphetamines. Amphetamines and other stimulant drugs have been extensively abused and the possibility of abuse of Phentermine should be kept in mind when evaluating the desirability of including a drug as part of a weight reduction program. Take fluvoxamine extended-release capsules at bedtime unless your doctor tells you otherwise. What are complications of depression? When these two medicines are taken together, your body may not process methadone properly. TiZANidine: CYP1A2 Inhibitors Strong may increase the serum concentration of TiZANidine. Management: Tizanidine use with ciprofloxacin or fluvoxamine is contraindicated. If use with another strong inhibitor cannot be avoided, initiate tizanidine at an adult dose of 2 mg and increase in 2-4 mg increments based on response. Monitor closely. What is the prognosis for depression? Read the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before you start taking fluvoxamine and each time you get a refill. If you have any questions, ask your doctor or pharmacist. nizoral
fluvoxamine online discount, fluvoxamine price in uk, fluvoxamine for locals, where to buy fluvoxamine in the uk, dollar fluvoxamine, how can i buy fluvoxamine, cost fluvoxamine pill, buy fluvoxamine australia online, fluvoxamine online payment buy now, fluvoxamine cheap purchase online, order fluvoxamine high, fluvoxamine pill, fluvoxamine tablets buy online shopping, purchase generic fluvoxamine, order generic fluvoxamine online usa, buy fluvoxamine in uk, cheapest fluvoxamine purchase pharmacy usa, cheap fluvoxamine order shop otc, best generic fluvoxamine, average price of fluvoxamine 100mg, where to buy fluvoxamine payment, mail order now fluvoxamine visa, can i buy fluvoxamine at costco, fluvoxamine buy pharmacy uk, generic fluvoxamine equate, pharmacy fluvoxamine manufacturer, pharmacy fluvoxamine reacoes, canada fluvoxamine prices, fluvoxamine generic drug, generic fluvoxamine buy pharmacy uk, what drugs limit fluvoxamine effectiveness, price of fluvoxamine cough syrup, order now cheap fluvoxamine payment, fluvoxamine costco, price of fluvoxamine 500mg, fluvoxamine order online shop australia, buy fluvoxamine 400 mg online, pharmacy fluvoxamine price, pharmacy support group fluvoxamine, order cheap fluvoxamine online canada, order fluvoxamine brands, generic fluvoxamine mexico, generic fluvoxamine pharmacy at home, money order fluvoxamine shopping otc, when will generic fluvoxamine be on the market, cheap fluvoxamine alternatives, fluvoxamine where to purchase uk, cheapest fluvoxamine order shop canada, price fluvoxamine in usa, buy fluvoxamine from shop, buy fluvoxamine singapore, fluvoxamine online australia legal, how can i purchase fluvoxamine, price of fluvoxamine in the uk, price fluvoxamine contraindicaciones, purchase generic fluvoxamine shop europe, buy fluvoxamine today, get your fluvoxamine ready, buy fluvoxamine online cheap, fluvoxamine prices pharmacy, buy cheapest fluvoxamine mastercard usa, buy fluvoxamine holland, cost fluvoxamine instrukcija, buy fluvoxamine online, fluvoxamine online japan, pharmacy fluvoxamine prices, price of fluvoxamine pills at walmart, fluvoxamine related drugs, generic fluvoxamine vs fluvoxamine, low cost fluvoxamine generic, great fluvoxamine, shop fluvoxamine capsules, buy fluvoxamine overseas, buy fluvoxamine from canadian pharmacy, order generic fluvoxamine shopping otc, buy fluvoxamine nyc, mail order generic fluvoxamine visa
St. John's wort and tryptophan. Caution is advised when using fluvoxamine extended-release capsules in the ELDERLY; they may be more sensitive to its effects, especially low blood sodium levels. Daniel DG, Randolph C, Jaskiw G, et al. Coadministration of fluvoxamine increases serum concentrations of haloperidol. J Clin Psychopharmacol 1994 Oct; 145: 340-3. order generic dapoxetine shopping otc
Decreased appetite and weight loss have been observed in association with the use of Fluvoxamine as well as other SSRIs. Consequently, regular monitoring of weight and growth is recommended if treatment of a child with an SSRI is to be continued long term. Warfarin and Other Drugs That Interfere With Hemostasis NSAIDs, Aspirin, etc. In in vitro studies, Fluvoxamine maleate had no significant affinity for histaminergic, alpha or beta adrenergic, muscarinic, or dopaminergic receptors. Antagonism of some of these receptors is thought to be associated with various sedative, cardiovascular, anticholinergic, and extrapyramidal effects of some psychotropic drugs. buy glucotrol from canadian pharmacy
Tell your doctor if your condition lasts or gets worse. Physicians' Desk Reference PDR. Abuse of amphetamines and related drugs may be associated with intense psychological dependence and severe social dysfunction. There are reports of patients who have increased the dosage of these drugs to many times than recommended. Abrupt cessation following prolonged high dosage administration results in extreme fatigue and mental depression; changes are also noted on the sleep EEG. Manifestations of chronic intoxication with anorectic drugs include severe dermatoses, marked insomnia, irritability, hyperactivity and personality changes. A severe manifestation of chronic intoxication is psychosis, often clinically indistinguishable from schizophrenia.
Phenytoin: FluvoxaMINE may increase the serum concentration of Phenytoin. If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Children younger than 8 years of age: Safety and efficacy have not been established.